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NWSPEC

Quaternary HPLC for Food Safety, Pharma & Environmental Analysis | LC20

Quaternary HPLC for Food Safety, Pharma & Environmental Analysis | LC20

LC20 Quaternary HPLC System

High-precision quaternary gradient system featuring UHPLC-derived pump technology (8,000 psi)

System Overview

High-precision quaternary HPLC engineered with an advanced UHPLC-derived pump architecture, 8,000 psi pressure range, 162-sample capacity, and ultra-low carryover (≤0.0005%). Built for high-reproducibility trace detection in pharmaceutical QC, food safety testing, and environmental monitoring.

Core Technology UHPLC-Derived Pump Architecture: Engineered for Superior Reliability

Unlike traditional HPLC pumps that operate near their mechanical limits, the LC20 quaternary pump is built on high-pressure UHPLC mechanical engineering. Featuring heavy-duty cam drives, floating piston seals, and micro-stroke delivery, the pump operates well within its design tolerances at 8,000 psi (55 MPa), delivering exceptional component longevity, ultra-flat baselines, and rock-solid flow stability (≤0.06% RSD).

✓ Heavy-Duty UHPLC Mechanics ✓ 8,000 psi Operating Headroom ✓ ≤0.06% RSD Flow Precision ✓ Minimized Dwell Volume & Fast Re-equilibration

Step 1: Select Pump Configuration

Standard System

Pressure: 7,800 psi (55 MPa)
Flow Range: 0.001–4.5 mL/min
Gradient: Quaternary (4 solvents)
Precision: ≤0.06% RSD
Select Standard

Advanced System

Recommended
Pressure: 8,000 psi (55 MPa)
Flow Range: 0.001–4.5 mL/min
Gradient: Quaternary + Smart Weighing
Precision: ≤0.06% RSD
Select Advanced

Step 2: Select Autosampler

Standard Autosampler

Capacity: 162 × 2 mL vials
Injection: 0.2–50 μL
Precision: ≤0.25% RSD
Carryover: ≤0.0005%
Select

Cooled Autosampler

+4°C
Capacity: 162 × 2 mL vials
Injection: 0.2–50 μL
Cooling: 4°C or 20°C below ambient
Carryover: ≤0.0005%
Select

Step 3: Select Detector(s)

Detector Wavelength/Range Best For Select
PDA (Photodiode Array)
Peak purity, spectral identification
 190–800 nm Method development, complex mixtures
UV/Vis
Routine quantitative analysis
 190–900 nm General purpose, high sensitivity
Fluorescence
Trace-level detection
 Ex: 200–750 nm
Em: 210–750 nm		 Low-concentration samples, biomarkers
Refractive Index (RID)
Universal detection
 1.00–1.75 RI Sugars, polymers, no chromophore
ELSD
Non-volatile compounds
 Light scattering Lipids, steroids, surfactants

Step 4: Add Options & Accessories

Column Oven

Ambient +4°C to 90°C, holds 3×300mm columns, 2 switching valves

External Degasser

4-channel vacuum degasser for mobile phase preparation

Seal Wash Kit

Extended pump life with high-salt mobile phases

Advanced Software Package

3D spectral mapping, automated method development tools

System Highlights

  • UHPLC-Derived Pump Mechanics: Built for high pressure and heavy-duty seal life
  • Quaternary Gradient: Four-solvent capability with ≤0.06% RSD flow precision
  • High Pressure: 8,000 psi operation for fast separations and long column life
  • Ultra-Low Carryover: ≤0.0005% for sensitive trace analysis
  • Sample Capacity: 162 vials or three 96-well plates
  • Zero Sample Loss: Needle-loading injection technology

Request a Quote & Technical Specifications

Configuring a new system or upgrading your analytical laboratory? Request pricing, configurations, and technical specifications within 24 hours.

Get Quote

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Since 1993 30+ Years of Instrument Expertise
Reliable Manufacturer Manufacturing & Services
Ph.D. Founded Dr. Pingxin Wang, UT Austin
Advantages Price · Service · Speed · Technical · Data
Fast Shipping In-Stock Orders Ship Same Day

Frequently Asked Questions

How can I contact you?

Feel free to call us T+86 189-6516-4839
or email  sales@nwspec.com to:

• Place an order
• Ask for a quote
• Or if you have any other questions

You will always get a live person here at NWSPEC; never an automated system! 

We are open from 6:00AM - 7:00PM Eastern Time, Monday - Friday. 

Where can I find application notes?

If you have any questions regarding the application notes, or can't find the one you are looking for, please contact Sales at sales@nwspec.com



Do you have instructional manuals for your instruments to download?

Yes, we have instructional manuals for our instruments. They can be found on https://nwspec.com/pages/resource .

If you don't see the one you are looking for, please contact: sales@nwspec.com



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